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T2584 |
Octreotide
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SMS 201-995 |
Somatostatin
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Octreotide (SMS 201-995) is a potent inhibitor of growth hormone, glucagon, and insulin. |
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TP2207 |
Pasireotide Acetate
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Somatostatin
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Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic |
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T9692 |
Paltusotine
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Somatostatin
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Paltusotine is a nonpeptide, small molecule somatostatin type 2 (SST2) receptor agonist with high oral bioavailability. Paltusotine maintains GH and IGF-1 levels in acromegaly patients |
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T4119 |
Octreotide Acetate
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SMS 201995,Longastatin,Sandostatin,SMS 201-995 (acetate) |
Somatostatin
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Octreotide Acetate (Sandostatin) is a potent, long-acting synthetic somatostatin octapeptide analog that inhibits secretion of growth hormone. |
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TP2045 |
CH 275
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Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin r... |
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T28743 |
Seglitide acetate
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MK 678,MK678,MK-678 |
Somatostatin
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Seglitide acetate (MK-678) is a selective agonist of sst2 somatostatin receptor. |
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TP2052L |
CTOP acetate
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Opioid Receptor
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CTOP acetate is a somatostatin analogue and a μ-opioid receptor antagonist. |
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TP1346 |
CYN 154806 TFA
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CYN 154806 TFA |
Somatostatin
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CYN 154806 TFA is a cyclic octapeptide and an effective selective somatostatin sst2 receptor antagonist. For the recombinant sst2, sst1, sst3, sst4 and sst5 receptors, the pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48... |
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T27787L |
L-797,591 hydrochloride
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L-797,591 hydrochloride(217480-24-5 Free base) |
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L-797,591 hydrochloride is active for somatostatin receptor isoform 1 (SSTR1). L-797,591 hydrochloride is commonly used in combination with AG1478 to enhance p-ERK5 expression in SSTR1 cells. L-797,591 hydrochloride sign... |
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TP2050L |
CTAP(TFA） (103429-32-9 free base)
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CTAP(TFA） |
Opioid Receptor
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CTAP(TFA) (103429-32-9 free base) is a potent, highly selective, and brain-penetrant antagonist of the μ-opioid receptor with IC50 of 3.5 nM. It displays over 1200-fold selectivity over δ opioid (IC50=4500 nM) and somato... |
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T22907 |
L-817,818
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Others
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somatostatin sst5 receptor agonist |
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T23073 |
NNC 26-9100
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Others
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Somatostatin sst4 receptor agonist |
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T28298 |
Pasireotide diaspartate
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SOM-230,SOM230,trade name: Signifor,SOM 230,Signifor LAR |
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Pasireotide is a somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs. |
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T27761 |
L-054,522
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L054,522 |
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L-054,522 is potent, selective agonists of somatostatin receptor. |
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T27783 |
L-779976
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L-779,976,L779,976,L779976,L 779976,L 779,976 |
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L-779,976 is an agonist of somatostatin receptor. |
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T31606 |
EE 581
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EE581,EE-581 |
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EE 581 can be used to label the somatostatin receptor. |
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T22487 |
(1R,1'S,3'R/1R,1'R,3'S)-L-054,264
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Others
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somatostatin sst2 receptor agonist |
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T27787 |
L-797,591
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L-797,591 is a selective agonist of somatostatin receptor subtype 1. |
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T24860 |
TC-G1003
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TC G1003 |
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TC-G1003 is an effective agonist of the somatostatin sst2 receptor. |
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T28220 |
NVP ACQ090
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NVP-ACQ090,ACQ090,ACQ 090,NVPACQ090,ACQ-090 |
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NVP ACQ090 is a potent and subtype-selective somatostatin sst(3) receptor antagonist. |
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T34592 |
Sdz 215-811
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Sdz-215-811,Pentatreotide,Sdz215-811,Octreoscan 111 |
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Sdz 215-811 is a potential radiopharmaceutical used in somatostatin receptor-positive tumors imaging. |
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T69836 |
Paltusotine HCl
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Paltusotine, also known as CRN00808, is a somatostatin receptor agonist. |
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T16469 |
Pentetreotide
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Others
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Pentetreotide is an indium-labeled somatostatin analog and can be used for nuclear medicine imaging. Pentetreotide is a diethylenetriaminopentaacetic conjugate of Octreotide. Somatostatin receptor scintigraphy with Pente... |
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TP1810 |
Somatostatin-25
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Somatostatin is an endogenous neuropeptide hormone found in the brain and pancreas. Somatostatin binds several isoforms of the somatostatin receptor, exhibiting anxiolytic, antiepileptic/anticonvulsant, and anorexigenic ... |
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T13306L2 |
Vapreotide diacetate
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Vapreotide diacetate is a synthetic analog of somatostatin. It has analgesic activity most likely mediated through the blockade of the neurokinin-1 receptor (NK1R), the substance P (SP)-preferring receptor. |
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T13005 |
SSTR5 antagonist 1
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Others
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SSTR5 antagonist 1 is a selective, and orally available antagonist of somatostatin receptor subtype 5 (SSTR5)(IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively). |
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T26225 |
SRA880 malonate
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SRA880,NVPSRA880,NVP-SRA880,NVP-SRA-880,NVP-SRA 880,NVP SRA880 |
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SRA880 is a non-peptide somatostatin sst(1) receptor antagonist which displays a significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d)= 6.0) or a wide range of neurotransmitter recep... |
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T76596 |
PRL 3195
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PRL 3195 is a somatostatin receptor antagonist, exhibiting K i values of 6, 17, 66, 1000, and 1000 nM for human somatostatin receptors sst 5 , sst 2 , sst 3 , sst 1 , and sst 4, respectively [1]. |
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T13022 |
SSTR5 antagonist 2
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Others
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SSTR5 antagonist 2 is a highly potent, oral active and selective antagonist of somatostatin (receptor) subtype 5 (SSTR5),with potential to treat type 2 diabetes mellitus (T2DM). |
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TP2124 |
Somatostatin 1-28
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Somatostatin receptor agonist, derived from the post-translational cleavage of prosomatostatin. |
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T39207 |
L-803087 TFA
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L-803087 TFA is a highly potent and selective agonist of the somatostatin sst4 receptor, exhibiting a Ki value of 0.7 nM. It displays a remarkable selectivity, being over 280-fold more preferential for the sst4 receptor ... |
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T28851 |
SRA880 free base
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SRA 880,NVPSRA880,NVP SRA880,NVP-SRA880,SRA-880,SRA880 |
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SRA880 is a non-peptide antagonist of somatostatin sst1-receptor. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0). SRA880 shows a certain binding a... |
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TP2420 |
Veldoreotide
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DG 3173,DG3173,PTR 3173,DG-3173,Somatoprim |
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Veldoreotide, also known as Somatoprim, is a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue which effectively reduces GH secretion in human GH-secreting pituitary adenomas, even in Octreotide non-r... |
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TP2050 |
CTAP
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Potent and selective μ opioid receptor antagonist (IC50 = 3.5 nM). Displays > 1200-fold selectivity over δ opioid and somatostatin receptors. Brain penetrant and active in vivo. |
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T75842 |
Cyclosomatostatin TFA
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Cyclosomatostatin TFA, a potent somatostatin (SST) receptor antagonist, inhibits type 1 somatostatin receptor (SSTR1) signaling, reducing cell proliferation, the size of the ALDH+ cell population, and sphere-formation in... |
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T13022L |
SSTR5 antagonist 2 TFA
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Others
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SSTR5 antagonist 2 TFA is a highly potent, oral active and selective antagonist of somatostatin (receptor) subtype 5 (SSTR5), with potential to treat type 2 diabetes mellitus (T2DM). |
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T76544 |
Cyclic SSTR agonist octreotide
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Cyclic SSTR agonist octreotide is a Octreotide , serving as the cyclic Somatostatin Receptor SSTR agonist [1] . |
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TP1877 |
CYN 154806
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CYN 154806 is a potent and selective somatostatin sst2 receptor antagonist, The pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively. |
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T11700 |
J-2156
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Others
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The ED50 of J-2156 in rats for the relief of mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws was 3.7 and 8.0 mg/kg, respectively. J-2156 is a high potent, selective somatostatin receptor type... |
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T76594 |
PRL 2915
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PRL 2915 is a potent antagonist of the human somatostatin subtype 2 receptor (hsst 2), exhibiting a binding affinity (K_i) of 12 nM [1]. |
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T32511L |
L-796,778 acetate
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L-796,778 acetate(217480-25-6 Free base) |
Somatostatin
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L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is >1000nM. |
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T75248 |
Pasireotide (diaspartate)
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Pasireotide diaspartate (SOM230), a long-acting cyclohexapeptide and somatostatin analog, enhances agonist activity across somatostatin receptor subtypes (sst1/2/3/4/5, with pK i values of 8.2, 9.0, 9.1, <7.0, and 9.9, r... |
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TP1804 |
PEN-221
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PEN-221 is a Somatostatin receptor 2 (SSTR2)-targeting cytotoxic conjugate with an IC50 of 10 nM. PEN-221 is a conjugate consisting of microtubule-targeting agent DM1 linked to the C-terminal side chain of Tyr3-octreotat... |
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T80157 |
DOTA-JR11
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DOTA-JR11 is a somatostatin receptor 2 (SSTR2) antagonist that can be radiolabeled with 68Ga. It is utilized for paired imaging in the study of neuroendocrine tumors (NETs) [1]. |
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T60784 |
SSTR4 agonist 2
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SSTR4 agonist 2 is a potent somatostatin receptor subtype 4 (SSTR4) agonist that has the potential in SSTR4-related medical disorders research. SSTR4 pathway inhibits the processes of nociceptive and inflammatory [1]. |
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T82883 |
BIM-23027
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BIM-23027 is a selective sst 2 receptor agonist (EC 50 = 0.32 nM) with effects analogous to the cyclic tetradecapeptide somatostatin (SRIF). It promotes dopamine release through a Glu-dependent mechanism [1] [2]. |
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T75917 |
CTAP TFA
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CTAP TFA, a potent and highly selective μ opioid receptor antagonist that effectively crosses the blood-brain barrier, exhibits a significant inhibition concentration (IC50) of 3.5 nM. It demonstrates extraordinary selec... |
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T76331 |
Cortistatin 29
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Cortistatin 29, a neuropeptide, alleviates neuropathic pain and exhibits anti-fibrotic effects. It binds with high affinity to all somatostatin (SS) receptor subtypes, displaying IC 50 values of 2.8 nM for SSTR1, 7.1 nM ... |
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T81571 |
PACAP (1-38) free acid TFA
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PACAP (1-38) free acid TFA, an endogenous neuropeptide, effectively enhances antral motility and somatostatin secretion, while concurrently suppressing gastrin secretion and promoting the release of vasoactive intestinal... |
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T76980 |
Tidutamab
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Tidutamab (XmAb-18087) is a bispecific antibody (bsAb) that is both humanized and optimized for affinity, targeting the SSTR2 and CD3 domains to bind to the somatostatin receptor 2 (SSTR2) and T cells, respectively. It f... |
